i haven't been seeing a ton of interest in my nobel prize posts, but i'm going to see this through the end of the week, so here goes.
the nobel prize in chemistry was awarded this morning to osamu shimomura, martin chalfie, and roger tsien "for the discovery and development of the green fluorescent protein, gfp." there is certainly no debate about the importance of gfp to molecular and cell biology research, and it is probably a very well deserved award, but for whatever reason, i'm a bit surprised by it. anyway...
...gfp was originally isolated from the jellyfish
aequorea victoria, and it was found that it's fluorescent qualities could be used in a variety of research applications, including the live imaging of cells and organisms. many bacteria, yeast, plant, fly, and mammalian cells, including human, have been created using gfp as a marker. the cells generally function normally, however, when exposed to a certain
wavelength of light, the gfp within the cells fluoresces. live fluorescence microscopy can be used to observe these cells over time, expressing one or more proteins tagged with gfp. cells labeled with gfp produce some incredible beautiful images.
hippocampal neuron expressing gfp

a moth expressing gfp in its eyes

mutations made to gfp have allowed for the creation of other fluorescent proteins, for example blue-, yellow-, and cyan-fluorescent proteins. here is a
confocal microscopy image of a mouse cerebral cortex, in which each neuron is randomly expressing a different gfp variant. the mouse is called the brainbow mouse.

although gfp is an incredibly important discovery, i bet the less biological, and more strictly chemistry chemists (e.g. organic, materials, physical, etc.) would like to see a few less nobels given for biochemical discoveries. it's just a hunch.